Question 1

Differentiate between the RBC characteristics associated with the various types of anemias,and identify the type of red blood cell associated with deficiency anemia.

Accepted Answer

A)   In deficiency anemia where there is a lack of iron or lack of copper, the RBCs are classified as microcytic hypochromic.
B)   In deficiency anemia where there is a lack of iron or lack of copper, the RBCs are classified as normocytic normochromic.
C)   In deficiency anemia where there is a lack of iron or lack of copper, the RBCs are classified as sickle-shaped microcytic.
D)   None of these are correct.E) B) and D)
F) A) and B)

Question 2

Identify the correct definition of the term hypochromic by breaking the word into its component parts.

Accepted Answer

A)   Hypo- refers to less than normal and -chromic means size.
B)   Hypo- refers to more than normal and -chromic means color.
C)   Hypo- refers to less than normal and -chromic means color.
D)   None of these are correct.E) B) and C)
F) A) and D)

Question 3

Identify the main function of hemoglobin in the prevention of anemia.

Accepted Answer

A)   The main function of hemoglobin is to stimulate the production of red blood cells in the bone marrow.
B)   The main function of hemoglobin is to stimulate the intestinal absorption of cyanocobalamin.
C)   The main function of hemoglobin is to transport oxygen to all of the tissues of the body.
D)   All of these are correct.E) None of the above
F) B) and D)

Question 4

Explain the reason why oral liquid iron supplements should be taken by straw or with juice or water.

Accepted Answer

A)   Liquid iron preparations should be taken with juice or water so that the iron does not erode the lining of the esophagus.
B)   Liquid iron preparations should be taken with juice or water or by straw to avoid or decrease the staining of the teeth.
C)   Liquid iron preparations should be taken with juice or water or by straw so that the iron does not come in contact with the tongue, causing glossitis.
D)   All of these are correct.E) All of the above
F) A) and B)

Question 5

Select the false statement about erythropoietin and its use.

Accepted Answer

A)   Erythropoietin is an enzyme produced in the liver that is necessary for the metabolic process of the body's cells.
B)   Erythropoietin stimulates production of red blood cells in the bone marrow.
C)   Erythropoietin production is impaired in patients who have renal failure, leading to erythropoietin deficiency.
D)   None of these are correct.E) None of the above
F) C) and D)

Question 6

Differentiate between normocytic and aplastic anemia,and select the true statement.

Accepted Answer

A)   Aplastic anemia is anemia in which RBCs are normal size and usually contain normal hemoglobin but are insufficient to carry adequate oxygen to the tissues (low RBC count) .Normocytic anemia is anemia caused by defective functioning of the
B)  blood-forming organs (Bone marrow) .
C)  Normocytic anemia is anemia in which RBCs are normal size and usually contain normal hemoglobin but are insufficient to carry adequate oxygen to the tissues (low RBC count) .Aplastic anemia is anemia caused by defective functioning of the
D)  blood-forming organs (bone marrow) .
E)  Normocytic anemia is anemia in which RBCs are normal size and usually contain normal hemoglobin but are insufficient to carry adequate oxygen to the tissues (low RBC count) .Aplastic anemia is anemia caused by large immature cells that cannot function as mature red blood cells.F) None of the above answers are correct.G) A) and D)
H) A) and B) B , D

Question 7

Summarize the special instructions associated with erythropoietin use.

Accepted Answer

A)   Preparations of erythropoietin cannot be frozen or vigorously shaken because the mechanical action will break (denature)  the glycoprotein.
B)   Erythropoietin should not be added to any other drug solution.
C)   Benzyl alcohol 0.9 percent may be added to the erythropoietin to minimize the discomfort at the injection site and act as a bacteriostatic agent.
D)   All of these are correct.E) All of the above
F) C) and D)

Question 8

Use your knowledge of the precautions and contraindications in the treatment of deficiency anemias to select the antidote for acute iron toxicity.

Accepted Answer

A)   Gastric lavage with 5 to 10 grams of deferoxamine mesylate
B)   Taking 200 mg of vitamin C orally within 10 minutes of the toxic dose
C)   Eating a meal to help bind the iron, preventing it from being absorbed into the bloodstream
D)   None of these are correctE) A) and D)
F) None of the above

Question 9

Describe a physiological situation that can lead to the development of anemia.

Accepted Answer

A)   Anemia may be caused by deficiency in the amount of hemoglobin, occurring when the number of circulating red blood cells is decreased.
B)   Anemia may be caused by an excessive loss of blood or an increased destruction of RBCs.
C)   Anemia may be caused by a decreased production of RBCs, which reduces the amount of circulating hemoglobin.
D)   All of these are correct.E) None of the above
F) B) and C) D

Question 10

Differentiate between the RBC characteristics associated with the various types of anemias,and identify the type of red blood cell associated with anemia due to increased red blood cell destruction.

Accepted Answer

A)   In anemia due to increased red blood cell destruction, the RBCs are classified as microcytic hypochromic.
B)   In anemia due to increased red blood cell destruction, the RBCs are classified as normocytic normochromic.
C)   In anemia due to increased red blood cell destruction, the RBCs are classified as hypochromic.
D)   None of these are correct.E) None of the above
F) B) and D)

Question 11

Use the contraindications profile of folic acid to select the false statement about its use.

Accepted Answer

A)   Administration of folic acid in a cobalamin deficiency will reverse the production of the megaloblastic cells, correcting the anemia.
B)   Folic acid has no effect on the synthesis of myelin.
C)   Folic acid can reverse the neurological changes associated with cobalamin deficiency, and the damage may continue until it becomes irreversible.
D)   Folic acid is not effective in the treatment of aplastic and normocytic anemias.E) B) and C)
F) A) and D)

Question 12

Explain what is meant by the term intrinsic factor.

Accepted Answer

A)   Intrinsic factor is a protein that is necessary for intestinal absorption of vitamin B12; lack of intrinsic factor leads to pernicious anemia.
B)   Intrinsic factor is an enzyme that is necessary for metabolism of vitamin B12; lack of intrinsic factor leads to pernicious anemia.
C)   Intrinsic factor is a protein that is necessary for intestinal absorption of vitamin B12; lack of intrinsic factor leads to megaloblastic anemia.
D)   None of these are correct.E) A) and D)
F) None of the above

Question 13

Use your knowledge of the treatments associated with deficiency anemias to explain to a patient why she cannot chew or crush an enteric-coated or delayed-release iron supplement.

Accepted Answer

A)   Sustained-release preparations should not be chewed or crushed because they will deliver more or all of the medication at once rather than over an extended period, causing a smooth, sore, beefy red tongue.
B)   Sustained-release preparations should not be chewed or crushed because they will deliver more or all of the medication at once rather than over an extended period, causing GI irritation because of the larger amount of iron released.
C)   Sustained-release preparations should not be chewed or crushed because they will deliver more or all of the medication at once rather than over an extended period, causing iron toxicity.
D)   All of these are correctE) A) and B)
F) A) and C)

Question 14

Differentiate between the treatment options for folic acid,iron,and vitamin B12 deficiency,and select the true statement related to these deficiencies.

Accepted Answer

A)   Erythropoietin therapy cannot reverse the effects of folic acid, iron, or vitamin B12 deficiency.
B)   Cyanocobalamin therapy is approved for the treatment of iron deficiency.
C)   Floic acid deficiency is associated with pernicious anemia and can be treated with cyanocobalamin.
D)   All of these are correctE) B) and D)
F) A) and C)

Question 15

Use your knowledge of deficiency anemias to select the true statement related to their treatment.

Accepted Answer

A)   Desferoxamine maleate can be used to treat zidovudine-related anemia in HIV patients.
B)   Folic acid can be used to treat aplastic anemia.
C)   Erythropoietin can be used to treat zidovudine-related anemia in HIV patients.
D)   Folic acid can be used to treat cobalamin deficiency.E) All of the above
F) None of the above

Question 16

Select the true statement related to treatment of anemia with the hematinics.

Accepted Answer

A)   Hematinics are available as over-the-counter products in tablet, capsule, and liquid forms.
B)   The addition of ascorbic acid (vitamin 
C)   enhances the intestinal absorption of iron.
C)   Long-term iron-deficient patients may require 100 to 200 mg of iron TID for at least 6 months. In comparison, iron deficiency associated with pregnancy, especially in the last trimester, may be corrected with 20 to 50 mg of iron.
D)   All of these are correct.E) None of the above
F) All of the above

Question 17

Use your knowledge of the treatments and interactions associated with deficiency anemias to explain to a patient why she should not take cimetidine within 2 hours of her cobalamin treatment.

Accepted Answer

A)   Cimetidine decreases gastric acid so that vitamin B12 cannot combine with available intrinsic factor, impairing but not totally inhibiting the absorption of vitamin B12.
B)   Cimetidine decreases gastric acid so that vitamin B12 cannot combine with available intrinsic factor, totally inhibiting the absorption of vitamin B12.
C)   Cimetidine decreases intrinsic factor production so that vitamin B12 cannot be absorbed.
D)   None of these are correct.E) B) and C)
F) A) and D) A

Question 18

Select the proper treatment for anemia resulting from altered RBC production or from increased RBC destruction.

Accepted Answer

A)   Replace iron or cyanocobalamin in the diet or supplementally.
B)   Replace iron or copper in the diet or supplementally.
C)   Give a blood transfusion.
D)   All of these are correct.E) A) and B)
F) A) and C)

Question 19

Describe the characteristics of a deficiency of cyanocobalamin.

Accepted Answer

A)  Cobalamin deficiency causes changes in all dividing cells,resulting in the production
B)  of macrocytes and megaloblasts.
C)  Cobalamin Deficiency causes changes in all dividing cells,resulting in the production of microcytes that are hypochromic.
D)  Cobalamin deficiency causes Changes in all dividing cells,resulting in the production
E)  of macrocytes that are normochromic.F) None of these are correct.G) D) and F)
H) A) and E)

Question 20

Select the statement that best describes how iron reaches the tissues and cells in the body.

Accepted Answer

A)   The plasma protein manufactured by the liver that delivers iron to tissues is called transferrin. It reversibly binds two ferric ions (Fe++)  absorbed from the intestine and macrophage activity and delivers them to other tissues.
B)   The plasma protein manufactured by the liver that delivers iron to tissues is called intrinsic factor. It reversibly binds two ferric ions (Fe++)  absorbed from the intestine and macrophage activity and delivers them to other tissues.
C)   The plasma protein manufactured by the liver that delivers iron to tissues is called folic acid. It reversibly binds two ferric ions (Fe++)  absorbed from the intestine and macrophage activity and delivers them to other tissues.
D)   None of these are correct.E) A) and D)
F) B) and C)

Exam 30: Antianemics

Differentiate between the RBC characteristics associated with the various types of anemias,and identify the type of red blood cell associated with deficiency anemia.

Correct AnswerverifiedShow Answer

Identify the correct definition of the term hypochromic by breaking the word into its component parts.

Correct AnswerverifiedShow Answer

Identify the main function of hemoglobin in the prevention of anemia.

Correct AnswerverifiedShow Answer

Explain the reason why oral liquid iron supplements should be taken by straw or with juice or water.

Correct AnswerverifiedShow Answer

Select the false statement about erythropoietin and its use.

Correct AnswerverifiedShow Answer

Differentiate between normocytic and aplastic anemia,and select the true statement.

Correct AnswerverifiedB , D

Summarize the special instructions associated with erythropoietin use.

Correct AnswerverifiedShow Answer

Use your knowledge of the precautions and contraindications in the treatment of deficiency anemias to select the antidote for acute iron toxicity.

Correct AnswerverifiedShow Answer

Describe a physiological situation that can lead to the development of anemia.

Correct AnswerverifiedD

Differentiate between the RBC characteristics associated with the various types of anemias,and identify the type of red blood cell associated with anemia due to increased red blood cell destruction.

Correct AnswerverifiedShow Answer

Use the contraindications profile of folic acid to select the false statement about its use.

Correct AnswerverifiedShow Answer

Explain what is meant by the term intrinsic factor.

Correct AnswerverifiedShow Answer

Use your knowledge of the treatments associated with deficiency anemias to explain to a patient why she cannot chew or crush an enteric-coated or delayed-release iron supplement.

Correct AnswerverifiedShow Answer

Differentiate between the treatment options for folic acid,iron,and vitamin B12 deficiency,and select the true statement related to these deficiencies.

Correct AnswerverifiedShow Answer

Use your knowledge of deficiency anemias to select the true statement related to their treatment.

Correct AnswerverifiedShow Answer

Select the true statement related to treatment of anemia with the hematinics.

Correct AnswerverifiedShow Answer

Use your knowledge of the treatments and interactions associated with deficiency anemias to explain to a patient why she should not take cimetidine within 2 hours of her cobalamin treatment.

Correct AnswerverifiedA

Select the proper treatment for anemia resulting from altered RBC production or from increased RBC destruction.

Correct AnswerverifiedShow Answer

Describe the characteristics of a deficiency of cyanocobalamin.

Correct AnswerverifiedShow Answer

Select the statement that best describes how iron reaches the tissues and cells in the body.

Correct AnswerverifiedShow Answer

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B , D

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D

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Differentiate between the treatment options for folic acid,iron,and vitamin B₁₂ deficiency,and select the true statement related to these deficiencies.

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A

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