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How are proteins digested and absorbed?

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Proteins are crushed and moistened in th...

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An otherwise healthy person regularly consuming a high-protein diet risks ________.


A) liver disease
B) decreased size of the liver and kidneys
C) dehydration
D) ulcers
E) diabetes

F) A) and D)
G) A) and C)

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Which amino acid may protect against heart disease by lowering blood pressure and preventing blood clots?


A) arginine
B) cysteine
C) tryptophan
D) phenylalanine
E) methionine

F) B) and D)
G) A) and D)

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What happens when pepsin enters the small intestine?


A) It activates HCl.
B) It is digested due to the high pH.
C) It cleaves proteins into smaller peptides and some free amino acids.
D) It inhibits pepsinogen synthesis.
E) It denatures protein structures.

F) A) and E)
G) B) and C)

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Which of the following statements about whey protein is FALSE?


A) It is popular among athletes hoping to build muscle.
B) It is found in many affordable protein powders.
C) It is a waste product of cheese production.
D) It benefits body tissues in ways dietary proteins cannot.
E) It has a high leucine content and is digested quickly.

F) B) and C)
G) A) and D)

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What component  denatures protein structures and activates pepsinogen?


A) hydrochloric acid
B) pepsin
C) trypsin
D) enteropeptidase
E) chymotrypsin

F) C) and E)
G) A) and E)

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Which of the following is the primary factor that differentiates one amino acid from another?


A) the side group
B) the central carbon atom
C) the amino group
D) the acid group
E) the presence of a central hydrogen atom

F) A) and B)
G) A) and C)

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Which of the following is NOT a function of proteins in the body?


A) providing fuel for energy needs
B) facilitating chemical reactions
C) maintaining volume of body fluids
D) protecting the body against diseases
E) inhibiting the absorption of cholesterol

F) C) and E)
G) B) and E)

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E

Which statement about protein transporters is FALSE?


A) Hemoglobin transports oxygen from the lungs to the cells.
B) Some transport proteins act as "pumps."
C) Iron is captured in an intestinal cell by a protein.
D) Transport proteins within a cell membrane pick up and release sodium and potassium across the membrane.
E) Active transport systems require no energy.

F) B) and E)
G) All of the above

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The incidence of PKU in the United States affects 1 in every _____ people.


A) 15,000
B) 100,000
C) 500,000
D) 10,000
E) 1,000,000

F) B) and C)
G) A) and E)

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Which of the following terms describes an amino acid that is normally dispensable, but must be supplied by the diet in special circumstances when the need for it exceeds the body's ability to make it?


A) conditionally nonessential amino acid
B) conditionally essential amino acid
C) nonessential amino acid
D) essential amino acid
E) circumspect amino acid

F) A) and B)
G) B) and C)

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Discuss three of the many roles of proteins in the body.

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From the moment of conception, proteins form the building blocks of muscles, blood, and skin-in fact, protein is the major structural component of all the body's cells. To build a bone or a tooth, for example, cells first lay down a matrix of the protein collagen and then fill it with crystals of calcium, phosphorus, magnesium, fluoride, and other minerals. Some proteins act as enzymes. Enzymes not only break down substances, but they also build substances (such as bone and transform one substance into another (amino acids into glucose, for example. Breaking down reactions are catabolic, whereas building up reactions are anabolic. The body's many hormones are messenger molecules, and some hormones are proteins. Various endocrine glands in the body release hormones in response to changes that challenge the body. The blood carries the hormones from these glands to their target tissues, where they elicit the appropriate responses to restore and maintain normal conditions. Proteins help to maintain the body's fluid balance. Normally, proteins are found primarily within the cells and in the plasma (essentially blood without its red blood cells. Being large, proteins do not normally cross the walls of the blood vessels. During times of critical illness or protein malnutrition, however, plasma proteins leak out of the blood vessels into the spaces between the cells. Because proteins attract water, fluid accumulates and causes swelling. Proteins also help to maintain the balance between acids and bases within the body fluids. Normal body processes continuously produce acids and bases, which the blood carries to the kidneys and lungs for excretion. The challenge is to maintain acid-base balance as conditions continually change. Some proteins move about in the body fluids, carrying nutrients and other molecules. The protein hemoglobin carries oxygen from the lungs to the cells. The lipoproteins transport lipids around the body. Special transport proteins carry vitamins and minerals. Proteins also defend the body against disease. A virus-whether it is one that causes flu, smallpox, measles, or the common cold-enters the cells and multiplies there. One virus may produce 100 replicas of itself within an hour or so. Each replica can then burst out and invade 100 different cells, soon yielding 10,000 viruses, which invade 10,000 cells. Left free to do their worst, they will soon overwhelm the body with disease. Fortunately, when the body detects these invading antigens, it manufactures antibodies, giant protein molecules designed specifically to combat them. The antibodies work so swiftly and efficiently that in a healthy individual, most diseases never get started. Without sufficient protein, though, the body cannot maintain its army of antibodies to resist infectious diseases. Without energy, cells die; without glucose, the brain and nervous system falter. Even though proteins are needed to do the work that only they can perform, they will be sacrificed to provide energy and glucose during times of starvation or insufficient carbohydrate intake. The body will break down its tissue proteins to make amino acids available for energy or glucose production (a process known as gluconeogenesis. In this way, protein can maintain blood glucose levels, but at the expense of losing lean body tissue. As mentioned earlier, proteins form integral parts of most body structures such as skin, muscles, and bones. They also participate in some of the body's most amazing activities such as blood clotting and vision. When a tissue is injured, a rapid chain of events leads to the production of fibrin, a stringy, insoluble mass of protein fibers that forms a solid clot from liquid blood. Later, more slowly, the protein collagen forms a scar to replace the clot and permanently heal the wound. The light-sensitive pigments in the cells of the eye's retina are molecules of the protein opsin. Opsin responds to light by changing its shape, thus initiating the nerve impulses that convey the sense of sight to the brain. The amino acids are as versatile as the proteins. In addition to serving as building blocks for proteins in the body, amino acids have multiple roles in regulating pathways that support growth, reproduction, metabolism, and immunity.

Which of the following proteins inactivates foreign bacteria and viruses?


A) enzymes
B) collagen
C) hormones
D) antibodies
E) antigens

F) A) and E)
G) C) and D)

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When amino acids are deaminated, the immediate products are ammonia and often a _____.


A) uric acid
B) keto acid
C) folic acid
D) gluco acid
E) fatty acid

F) A) and C)
G) C) and D)

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B

A vegetarian who plans a meal involving black beans can consume all the essential amino acids by adding another a plant protein rich in ________.


A) lysine
B) tyrosine
C) methionine
D) isoleucine
E) phenylalanine

F) A) and C)
G) C) and D)

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The protein RDA for adults is ________ grams per kilogram of body weight.


A) 0.08
B) 0.36
C) 0.8
D) 3.6
E) eight

F) A) and C)
G) B) and C)

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In what part of the GI tract is pepsin active?


A) mouth
B) stomach
C) pancreas
D) small intestine
E) liver

F) B) and C)
G) C) and E)

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Which of the following would NOT be classified as a carcinogen by the World Health Organization?


A) bacon
B) hot dogs
C) beef jerky
D) chicken
E) ham

F) B) and E)
G) B) and D)

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Transamination produces a new nonessential amino acid and a new ________.


A) uric acid
B) keto acid
C) folic acid
D) gluco acid
E) phyto acid

F) A) and B)
G) C) and D)

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The process of messenger RNA being made from a template of DNA is ________.


A) expression
B) sequencing
C) transcription
D) ribosome assembly
E) translation

F) B) and D)
G) C) and E)

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